Sibi Joseph
Department of Neurology, Nelson Mandela Academic Hospital, South AfricaPublications
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Research Article
Dercum?s Disease with Associated with Autonomic Manifestations, Novel Hypotheses on Pathophysiology of Neuritic Pain and Drug Therapy
Author(s): Lourdes de Fatima Ibanez Valdes, Sibi Joseph and Humberto Foyaca Sibat*
Introduction: Dercum’s Disease (DD), also named Adiposis Dolorosa (AD). It is a chronic debilitating condition with various clinical presentation types confirmed through imaging. It is a sporadic syndrome characterized by multiple, painful, subcutaneous adipose tissues commonly localized in the abdomen and extremities. We reported a new case presenting different neurological manifestations. Methods: We searched the literature, following the guidelines outlined in the PRISMA statement. From January 2023 to January 2025, the authors searched the scientific databases, Scopus, Embassy, Medline, and PubMed Central using the following searches: “Dercum’s disease” OR “adiposis dolorosa” OR “Pathophysiology of neuritic pain” OR “neuritic pain in adiposis dolorosa” OR “therapy of Dercu.. Read More»