Donna Adriani

Department of Phisiology, Universitas Trisakti, Indonesia

Publications

• Review   
  The Effectiveness of using Mefenamic Acid Drug against Primary Dysmenorrhea in Female Adolescents
  Author(s): Ubaid Fuad Frahman and Donna Adriani*
  
  Menstrual pain or dysmenorrhea is a gynecological problem in women of all ages, specifically adolescents. Approximately 90% of female adolescents experience menstrual problems, with over 50% of these being dysmenorrhea, which can be divided into primary and secondary types. Furthermore, secondary dysmenorrhea is caused by abnormalities in the genital organs. At the onset of menstruation, there is a decrease in the levels of prostaglandins and estradiol, which leads to the formation of arachidonic acid. Subsequently, this acid is converted into prostaglandins, prostacyclin, thromboxane A2, and Cyclooxygenase (COX). The substances stimulate the work of the uterine muscles, resulting in increased contractions. The pain felt is usually concentrated in the suprapubic area and can be accompanied by other disorders such as digestive problems, nausea, vomit.. Read More»
  DOI: 10.4303/JDAR/236231

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