Suhasin Ganta

Department of Pharmacology, GITAM Institute of Pharmacy, GITAM (Deemed to be University), Visakhapatnam, A.P, India

Publications

• Research Article   
  Ethanolic Leaf Extract of Moringa Oleifera A Potential Agent For Treatment Of Hemorrhoids: And Its Evaluation in Croton Oil Induced Hemorrhoidal Rats
  Author(s): Sai Krishna Nallajerla* and Suhasin Ganta
  
  Hemorrhoids are gastro intestinal disorders associated with engorged venous cushions in the anal canal. Protrusion of anal cushions, rectal bleeding, irritation, and mucus discharge from the anus are the major symptoms of the disease. Inflammation remains to be one of the pathogenic mechanisms for the development of disease. Hence, in the present study, the ethanolic leaf extract of Moringa oleifera (ELEMO) in two different doses, 200 mg/kg/ir and 400 mg/kg/ir, was evaluated for its anti-inflammatory mediated anti-hemorrhoidal effect in croton oil induced hemorrhoidal rats. The study results revealed that intra rectal application of croton oil preparation in albino rats induces hemorrhoids by the elevation of serum pro-inflammatory cytokines, TNF-α, and IL-6 in group-II positive control animals. Whereas, ELEMO treatment in group IV and V.. Read More»
  DOI: 10.4303/jdar/236189

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