Paola Fasciani

Department of UOC Servizi Dipendenze, ASL Lanciano Vasto Chieti, Italy


  • Research Article   
    Levomethadone Safety Profile and Effectiveness in Subjects under Opioid Maintenance Treatment: An Observational, Prospective Study
    Author(s): Augusto Consoli*, Paola Fasciani, Emilio Vanoli and Marco Riglietta

    Purpose: To provide further data on the safety and effectiveness of levo- methadone after its long term use in a real world setting, an observational study involving opioid addicted patients undergoing maintenance treat- ment with levomethadone is ongoing in Italy (LEVOPROACT study). This work provides the results of the interim analysis after 2 years from the first site activation. Methods: This is a prospective, observational, non-interventional, open ended study conducted in ten Italian centers and involving patients aged ≥18 years with a diagnosis of opioid addiction (ICD-10 F11.2), initiating or currently undergoing levomethadone maintenance treatment as for routine medical practice. Results: Long term levomethadone therapy is effective in the treatment of opioid addiction, with a reduction in craving and .. Read More»

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