Lourdes de Fatima Ibanez Valdes
Department of Neurology, Walter Sisulu University (WSU), South AfricaPublications
-
Research Article
Update Information on Locked-In Syndrome, Drug Therapy and Comprehensive Review
Author(s): Lourdes de Fatima Ibanez Valdes* and Humberto Foyaca Sibat
Introduction: Locked?in Syndrome (LIS) is characterised by anarthria, cranial nerve palsies, and quadriplegia, with a normal level of consciousness, awareness without cognitive decline, regular eyelid movements, preserved vertical gaze movements, hearing, and proper breathing. In patients with LIS, cognitive function may be affected, depending on the nature of the lesion; the brainstem is the most common post?injury site, while awareness and arousal remain intact. Objectives: This comprehended literature study aimed to search for studies related with the emerging and novel therapies for LIS. Methods: We search the EMBASE, Scopus, and Medline, databases, to identify case reports, case series, clinical trials in patients of any sex, race, age, or ethnicity who received any approved or experimental treatment for LIS. .. Read More»
DOI: 10.4303/JDAR/236479
