Hemant K.Sharma
College of Pharmacy, Sri Satya Sai University of Technology and Medical Sciences, India, IndiaPublications
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Research Article
Stability Indicative and Cost Effective Analytical Method Development and Validation Of Favipiravir and Oseltamivir in Bulk And Pharmaceutical Dosage Form By Using Rp-Hplc
Author(s): A .Venkata Suresh Babu* and Hemant K.Sharma
The current investigation was pointed at developing and progressively validating novel, simple, responsive and stable RP-HPLC method for the measurement of active pharmaceutical ingredients of Favipiravir and Oseltamivir and their related substances. A simple, selective, validated and well-defined stability that shows gradient RP-HPLC methodology for the quantitative determination of Favipiravir and Oseltamivir. The chromatographic strategy utilized Column of Dikma Inspire (4.6 mm × 250 mm, 5mm), using isocratic elution with a mobile phase of 0.1% orthophosphoric acid and Acetonitrile (83:37). A flow rate of 1 ml/min and a detector wavelength of 254 nm utilizing the 2487 UV detector were given in the instrumental settings. Using the impurity-spiked solution, the chromatographic approach was streamlined. Validation of the proposed method was carri.. Read More»
DOI: 10.4303/jdar/236196