Bharghava Bhushan Rao
Department of Pharmaceutics, A M Reddy Memorial College of Pharmacy, IndiaPublications
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Research Article
Drug Formulation and Characterization of Multiple Emulsion System Containing Olive Oil and Two Antiaging Agents in Drug Content
Author(s): Shaik Harun Rasheed*, Sayyad Mustak, Gampa Vijay Kumar, Bharghava Bhushan Rao, Naidu Narapusetty, Jhansi Priya Marabathuni and Laith Hamza Samein
The intention of the study was to formulate a stable multiple emulsion system containing 2 skin antiaging agents using a natural oil vitamin C, known to be a very unstable ingredient and is decomposed in the presence of oxygen, was entrapped in the internal aqueous phase of w/o/w multiple emulsion. In this way, vitamin C is expected to exhibit slow release and the effect of vitamin C can be improved as it has been protected from the external environment. The other ingredient, which is a product of wheat protein was also used as an antiaging agent. Both of the ingredients increase the synthesis of collagen fibers in the dermis. Therefore, a synergistic effect can be produced by using the 2 ingredients in 1 formulation. In this study, multiple emulsions were prepared by the two-step emulsification method. Basic formulation containing no active material and a formulation containing vitam.. Read More»
DOI: 10.4303/JDAR/236232