Yousef JavadzadehDepartment of Pharmaceutics, Tabriz University of Medical Sciences, Iran
Does Alcohol Able to Change Pharmacokinetics of Drugs in Alcoholic People?
Author(s): Salar Masoomzadeh and Yousef Javadzadeh*
Introduction: Alcohol is a commonly used drink worldwide. Its consumption increases after addiction as a result of long-term regular heavy drinking; heavy alcohol intakes can cause fatal injuries affecting the brain, the heart and directly affect the enzymes in the body, interfering with the pharmacokinetics of the drugs sharing the same enzyme for metabolism, and may reduce or increase the effectiveness of the drugs; these changes can occur due to different reasons like the change in the absorption of the drug, distribution, metabolism or excretion, and elimination. Using ethanol (EA) along with medications can cause changes in alcohol metabolism too so it may cause alcohol toxicity. The current study aims to review the recently available data about these topics to discuss the ethanol-drugs reaction. Methods: Related articles using &.. Read More»