The Role of Rouget Cells in Neurocysticercosis

Author(s): Lourdes de Fatima Ibanez Valdes*


Background: Neurocysticercosis (NCC) is a zoonotic, preventable, and eradicable parasitic disease secondary to the infection by the larva form of pig tapeworm Taenia solium (Ts) mainly in underdeveloped countries. However, the number of carriers in developed countries is increasing gradually due to globalization and uncontrolled migration.

In this study, we look for a manuscript related to the role played by Rouget cell (pericytes) in the pathogenesis of NCC in the cerebral hemispheres and spinal cord. After reviewing this matter, we formulate some hypotheses regarding its role in NCC.

Method: We searched medical literature, looking for published Medical Subject Heading (MeSH) terms like “Neurocysticercosis,” “pathogenesis of Neurocysticercosis,” “comorbidity in NCC” OR “Rouget cell (RC)” OR “Pericytes (PC)” OR “PC/Oligodendrocyte Precursor Cells (OPC)”; OR “Epileptic Seizures (ES)/Secondary Epilepsy (SEp)/NCC/RC-PC” OR “RC-PC/ES/SEp”; OR “RC-PC/BBB/NCC.”

Results: All selected manuscripts were peer-reviewed, and we did not find any publication related to RC-PC/NCC.

Comments and concluding remarks: We have hypothesized the role played by RC-PC on the pathogenesis of cysticercus perilesional oedema and the role of RC-PC on the pathogenesis of ES/SEp/NCC.

image 10.4303/JDAR/236289

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