Neuropsychiatric Manifestations of Neurocysticercosis: A Comprehensive Review

Author(s): Ibanez-Valdes Lourdes de Fatima, Thozama Dubula and Foyaca-Sibat Humberto*


Background: Cysticercosis (Ct) is a preventable and eradicable zoonotic parasitic disease secondary to an infection caused by the larva form of pig tapeworm Taenia solium (Ts), usually seen in people living in developing countries. However, the number of carriers in developed countries increases gradually due to globalization and uncontrolled migration. In this study, we look for information related with the pathogenesis of neuropsychiatric manifestation in patients with neurocysticercosis (NPNCC).

Method: We searched the medical literature comprehensively, looking for published Medical Subject Heading (MeSH) terms like “neurocysticercosis,” “pathophysiology of NPNCC,” “immunology of NPNCC” OR “dysfunctional mitochondria in NPNCC” “dysbiosis in NPNCC.”

Results: All selected manuscripts were peer-reviewed, and we did not find publications related to pathophysiology of NPNCC.

Comments and concluding remarks: We hypothesized the role-played dysfunctional mitochondria, neuroinflammation, dysbiosis on the pathogenesis of NPNCC.

image 10.4303/JDAR/236253

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